Rab7A is required for efficient production of infectious HIV-1.

Retroviruses take advantage of cellular trafficking machineries to assemble and release new infectious particles. Rab proteins regulate specific steps in intracellular membrane trafficking by recruiting tethering, docking and fusion factors, as well as the actin- and microtubule-based motor proteins...

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Bibliographic Details
Main Authors: Marina Caillet, Katy Janvier, Annegret Pelchen-Matthews, Delphine Delcroix-Genête, Grégory Camus, Mark Marsh, Clarisse Berlioz-Torrent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002347&type=printable
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