Targeting the Hepcidin-Ferroportin Axis in the Diagnosis and Treatment of Anemias
The hepatic peptide hormone hepcidin regulates dietary iron absorption, plasma iron concentrations, and tissue iron distribution. Hepcidin acts by causing the degradation of its receptor, the cellular iron exporter ferroportin. The loss of ferroportin decreases iron flow into plasma from absorptive...
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2010/750643 |
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