A multi-tissue atlas of allelic-specific expression reveals the characteristics, mechanisms, and relationship with dominant effects in cattle

A multi-tissue atlas of allelic-specific expression reveals the characteristics, mechanisms, and relationship with dominant effects in cattle

Abstract Background Allele-specific expression (ASE) analysis is a crucial tool for validating expression quantitative trait loci (eQTLs), identifying causal variants associated with complex traits, and investigating the genetic mechanisms underlying heterosis. In this study, we characterized ASE va...

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Bibliographic Details
Main Authors: Jiaqi Li, Lei Xu, Xiaoyun Liang, Letian Li, Frederic Farnir, Xixia Huang, Qiuming Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Biology
Subjects:
Allele-specific expression
Cattle
Dominant effect
Online Access:https://doi.org/10.1186/s12915-025-02257-0
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https://doi.org/10.1186/s12915-025-02257-0

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