Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway

Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway

Introduction: Metabolic syndrome is a serious public health concern across the globe. However, the typical metabolites and mechanisms underlying the decreased fertility related to metabolic syndrome is still elusive. Objectives: The aim of the present study was to explore the typical metabolites and...

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Main Authors: Xiangzhou Zeng, Xinyin Fan, Haitao Yu, Shuang Cai, Liangrui Zhou, Huanwen Wu, Zhiwen Zhang, Shuang Quan, Siyu Li, Xinyu Wang, Bangxin Xue, Lu Liu, Shiyan Qiao, Xiangfang Zeng
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Advanced Research
Subjects:
Ovarian dysfunction
Metabolic syndrome
Inflammation
Mitochondrial oxidative stress
Nervonic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224003710
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