Exosomes and MicroRNAs: key modulators of macrophage polarization in sepsis pathophysiology

Exosomes and MicroRNAs: key modulators of macrophage polarization in sepsis pathophysiology

Abstract Sepsis is a highly dangerous and complex condition that can result in death. It is characterized by a strong reaction to an infection, causing dysfunction in multiple bodily systems and a high risk of mortality. The transformation of macrophages is a vital stage in the procedure as they pos...

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Main Authors: Mohamed J. Saadh, Tamara Nazar Saeed, Karar H. Alfarttoosi, Gaurav Sanghvi, R. Roopashree, Vishal Thakur, L. Lakshmi, Aziz Kubaev, Waam Mohammed Taher, Mariem Alwan, Mahmood Jasem Jawad, Ali M. Ali Al-Nuaimi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:European Journal of Medical Research
Subjects:
Sepsis
Macrophage polarization
MicroRNA
Exosome
Online Access:https://doi.org/10.1186/s40001-025-02561-z
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https://doi.org/10.1186/s40001-025-02561-z

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