Aging and IGF-I: relationships with vitamin D and body composition. A mediation analysis

Aging and IGF-I: relationships with vitamin D and body composition. A mediation analysis

BackgroundInsulin-like Growth Factor I (IGF-I) and Vitamin D are crucial for growth and metabolism, with their levels declining with age. However, their mutual interactions and contributions to body composition remain unclear.ObjectivesTo examine the relationships between IGF-I, Vitamin D, and body...

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Main Authors: Roberto Vicinanza, Alessandro Frizza, Julie A. Pollard, Valentina Mazza, Massimo Ulderico De Martino, Giovanni Imbimbo, Pasquale Pignatelli, Evaristo Ettorre, Maria Del Ben, Alessio Molfino
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Nutrition
Subjects:
aging
body composition
fat-free mass
frailty
IGF-I
insulin-like growth factor-I
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1585696/full
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https://www.frontiersin.org/articles/10.3389/fnut.2025.1585696/full

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