Deep learning-based high-resolution time inference for deciphering dynamic gene regulation from fixed embryos

Abstract Embryo development is driven by the spatiotemporal dynamics of complex gene regulatory networks. Uncovering these dynamics requires simultaneous tracking of multiple fluctuating molecular species over time, which exceeds the capabilities of traditional live-imaging approaches. Fixed-embryo...

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Bibliographic Details
Main Authors: Huihan Bao, Shihe Zhang, Zhiyang Yu, Heng Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61907-7
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