A computational study exploring echinoderm-derived compounds for inhibition of aminoglycoside acetyltransferases.

Aminoglycoside acetyltransferases (AACs) catalyze the acetylation of aminoglycoside antibiotics, playing a major role in bacterial resistance and posing a serious threat to global healthcare. Despite growing interest in natural products, echinoderm-derived metabolites remain largely unexplored as AA...

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Bibliographic Details
Main Authors: Abdullah R Alanzi, Moneerah J Alqahtani, Jawaher H Alqahtani, Hattan A Alharbi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0327409
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