Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy

BACKGROUND: Serum tumour necrosis factor-alpha (TNF-α) levels correlate negatively with hepatitis C virus (HCV) antiviral response.

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Main Authors: Curtis Cooper, Stephen Shafran, Susan Greenbloom, Robert Enns, John Farley, Nir Hilzenrat, Kurt Williams, Magdy Elkashab, Nabil Abadir, Manuela Neuman
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2014/367131
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author Curtis Cooper
Stephen Shafran
Susan Greenbloom
Robert Enns
John Farley
Nir Hilzenrat
Kurt Williams
Magdy Elkashab
Nabil Abadir
Manuela Neuman
author_facet Curtis Cooper
Stephen Shafran
Susan Greenbloom
Robert Enns
John Farley
Nir Hilzenrat
Kurt Williams
Magdy Elkashab
Nabil Abadir
Manuela Neuman
author_sort Curtis Cooper
collection DOAJ
description BACKGROUND: Serum tumour necrosis factor-alpha (TNF-α) levels correlate negatively with hepatitis C virus (HCV) antiviral response.
format Article
id doaj-art-86d716f953a848e887b86bf777a0cec6
institution Kabale University
issn 2291-2789
2291-2797
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-86d716f953a848e887b86bf777a0cec62025-02-03T01:12:15ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972014-01-01281354010.1155/2014/367131Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin TherapyCurtis Cooper0Stephen Shafran1Susan Greenbloom2Robert Enns3John Farley4Nir Hilzenrat5Kurt Williams6Magdy Elkashab7Nabil Abadir8Manuela Neuman9University of Ottawa, Ottawa Hospital Research Institute, Ottawa, Ontario, CanadaUniversity of Alberta, Edmonton, Alberta, CanadaToronto Digestive Disease Associates, Toronto, Ontario, CanadaSt Paul’s Hospital, University of British Columbia, CanadaPrivate Practice, Vancouver, British Columbia, CanadaJewish General Hospital and McGill University, Montreal, Quebec, CanadaRoyal University Hospital, Saskatoon, Saskatchewan, CanadaPrivate practice, Toronto, Ontario, CanadaMerck Canada Inc, Kirkland, Quebec, CanadaUniversity of Toronto, Toronto, Ontario, CanadaBACKGROUND: Serum tumour necrosis factor-alpha (TNF-α) levels correlate negatively with hepatitis C virus (HCV) antiviral response.http://dx.doi.org/10.1155/2014/367131
spellingShingle Curtis Cooper
Stephen Shafran
Susan Greenbloom
Robert Enns
John Farley
Nir Hilzenrat
Kurt Williams
Magdy Elkashab
Nabil Abadir
Manuela Neuman
Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
Canadian Journal of Gastroenterology and Hepatology
title Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_full Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_fullStr Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_full_unstemmed Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_short Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_sort single dose infliximab in hepatitis c genotype 1 treatmentnaive patients with high serum levels of tumour necrosis factor alpha does not influence the efficacy of pegylated interferon alpha 2b ribavirin therapy
url http://dx.doi.org/10.1155/2014/367131
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