Egg-driven immunosuppression and granuloma zonation in Peyer’s patches of mice with Schistosoma japonicum infection

Egg-driven immunosuppression and granuloma zonation in Peyer’s patches of mice with Schistosoma japonicum infection

Egg granulomas caused by Schistosoma japonicum (S. japonicum) are important causes of morbidity and mortality in schistosomiasis. The intestine plays a crucial role in the complete life cycle of S. japonicum; eggs are transported through the intestine and excreted with feces. During this process, th...

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Main Authors: Linzhu Li, Jing Wu, Guangxu Cao, Jiakai Yao, Yanping Miao, Yanglin Zhuang, Yushen Xiang, Xiaolin Zhong, Yicong Liu, Fubo Chen, Yalei Dai, Yang Dai, Xindong Xu, Qingfeng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Schistosoma japonicum
granuloma
Peyer’s patch
immunosuppression
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1587166/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1587166/full

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