IRON METABOLISM IN THALASSEMIA AND SICKLE CELL DISEASE

There are two main mechanisms by which iron overload develops in thalassemias: increased iron absorption due to ineffective erythropoiesis and blood transfusions. In nontransfused patients with severe thalassemia, abnormal dietary iron absorption increases body iron burden between 2 and 5 g per year...

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Bibliographic Details
Main Authors: Raffaella Mariani, Paola Trombini, Matteo Pozzi, Alberto Piperno
Format: Article
Language:English
Published: PAGEPress Publications 2009-10-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
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Online Access:http://www.mjhid.org/index.php/mjhid/article/view/120
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