The relative resistance of children to sepsis mortality: from pathways to drug candidates
Abstract Attempts to develop drugs that address sepsis based on leads developed in animal models have failed. We sought to identify leads based on human data by exploiting a natural experiment: the relative resistance of children to mortality from severe infections and sepsis. Using public datasets,...
Saved in:
| Main Authors: | Rose B Joachim, Gabriel M Altschuler, John N Hutchinson, Hector R Wong, Winston A Hide, Lester Kobzik |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2018-05-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.20177998 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of Potential Sepsis Therapeutic Drugs Using a Zebrafish Rapid Screening Approach
by: Mark Widder, et al.
Published: (2024-12-01) -
Identifying early predictive and diagnostic biomarkers and exploring metabolic pathways for sepsis after trauma based on an untargeted metabolomics approach
by: Yi Gou, et al.
Published: (2025-04-01) -
Intestinal injury signaling pathway in sepsis
by: Lin Liu, et al.
Published: (2025-06-01) -
Candidal sepsis thoracic patient
by: V. I. Desyaterik, et al.
Published: (2019-08-01) -
The association of sepsis bundle compliance with mortality in patients with ICU-acquired sepsis: a cohort study
by: Adam Green, et al.
Published: (2025-05-01)