The relative resistance of children to sepsis mortality: from pathways to drug candidates

Abstract Attempts to develop drugs that address sepsis based on leads developed in animal models have failed. We sought to identify leads based on human data by exploiting a natural experiment: the relative resistance of children to mortality from severe infections and sepsis. Using public datasets,...

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Bibliographic Details
Main Authors: Rose B Joachim, Gabriel M Altschuler, John N Hutchinson, Hector R Wong, Winston A Hide, Lester Kobzik
Format: Article
Language:English
Published: Springer Nature 2018-05-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20177998
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