Regulation of FOXL2 gene in ovarian granulosa cell tumor by JNK inhibitor

Abstract To explore the regulatory effect of c-Jun N-terminal kinase (JNK) inhibitor (SP600125) on forkhead box protein L2 (FOXL2) gene in human ovarian granulosa cell tumor cells (KGN cells). The main pathogenic gene FOXL2 of ovarian cancer was screened by bioinformatics method. KGN cells were rand...

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Bibliographic Details
Main Authors: Yuzhu Zhang, Yu Wang, Yuan Gu, Yang Liu, Guohua Liu, Jun Wu, Nan Bai
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85439-8
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