Next-Generation Sequencing–Based Molecular Profiling of Conjunctival Squamous Cell Carcinoma and Its Potential Application for Therapy

Next-Generation Sequencing–Based Molecular Profiling of Conjunctival Squamous Cell Carcinoma and Its Potential Application for Therapy

Objective: Targeted next-generation sequencing–based genomic and transcriptomic analyses of conjunctival squamous cell carcinoma (cSCC) samples using a panel of >1700 cancer-related genes. Design: Prospective case series. Participants: Twenty patients with invasive cSCC consecutively managed at a...

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Bibliographic Details
Main Authors: Hakan Demirci, MD, Josh N. Vo, PhD, Yi-Mi Wu, PhD, Victor Elner, MD, Arul M. Chinnaiyan, MD, PhD, Dan Robinson, PhD, F. Yesim Demirci, MD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ophthalmology Science
Subjects:
Copy number alterations
Mutations
Tumor mutation burden
UV signature
Conjunctival squamous cell carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914525000995
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