Unveiling the anticancer potential of Curcuma amada rhizome extract against prostate cancer through computational and experimental approaches

Unveiling the anticancer potential of Curcuma amada rhizome extract against prostate cancer through computational and experimental approaches

Abstract Prostate cancer (PCa), a common urinary malignancy, is the leading cause of mortality and morbidity among men worldwide. Curcuma amada extract has demonstrated antitumor properties in preclinical models of various cancers, however, its mechanisms against prostate cancer remain unclear. The...

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Main Authors: Arpita Priyadarshini, Debajani Mohanty, Swagat Mohanty, Rout George Kerry, Ambika Sahoo, Biswabhusan Dash, Pratap Chandra Panda, Sanghamitra Nayak, Asit Ray, Sudipta Jena
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Curcuma amada
Molecular docking
Molecular dynamics simulation
Network pharmacology
Prostate cancer
UHPLC-QTOF-HRMS/MS
Online Access:https://doi.org/10.1038/s41598-025-10761-0
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https://doi.org/10.1038/s41598-025-10761-0

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