Imidazolium salts carrying two positive charges: design, synthesis, characterization, molecular docking, antibacterial and enzyme inhibitory activities

Imidazolium salts carrying two positive charges: design, synthesis, characterization, molecular docking, antibacterial and enzyme inhibitory activities

IntroductionThe discovery of alternative drugs has gained importance due to the many side effects of these drugs used for treatment.MethodsHerein, the synthesis of a series of unsymmetrical imidazolium salts containing 4-acetylphenyl/4-formylphenyl and bioactive heterocyclic groups such as morpholin...

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Main Authors: Ilter Demirhan, Adem Necip, Erkan Oner, Nalin Gumuscu, Ozlem Demirci, Yetkin Gok, Nebiye Yentur Doni, Mesut Işık, Mithun Rudrapal, Johra Khan, Randa Mohammad Ibrahim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
N-heterocyclic carbene
imidazolium salt
acetylcholinesterase
antimicrobial
anti-Alzheimer
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1579916/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1579916/full

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