Topical adhesive spatio-temporal nanosystem co-delivering chlorin e6 and HMGB1 inhibitor glycyrrhizic acid for in situ psoriasis chemo-phototherapy

Topical adhesive spatio-temporal nanosystem co-delivering chlorin e6 and HMGB1 inhibitor glycyrrhizic acid for in situ psoriasis chemo-phototherapy

Recently, photodynamic therapy (PDT) has gained considerable attention as a promising therapeutic approach for the treatment of psoriasis. Unfortunately, the activation of high mobility group box 1 protein (HMGB1) by PDT triggers innate and adaptive immune responses, which exacerbate skin inflammati...

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Bibliographic Details
Main Authors: Lijun Su, Yixi Zhu, Xuebo Li, Di Wang, Xiangyu Chen, Zhen Liu, Jingjing Li, Chen Zhang, Jinming Zhang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Psoriasis
Chitosan
Catechol
Spatio-temporal nanosystem
Glycyrrhizic acid liposome
Chemo-phototherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524004775
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