Reversing the “cold” tumor microenvironment: the role of neoantigen vaccines in prostate cancer
Abstract Background Prostate cancer (PCa) is a common malignancy with a “cold” tumor microenvironment (TME) that limits immunotherapy efficacy. Neoantigens from non-synonymous mutations are potential immunotherapeutic targets. Methods We identified the neoantigens map in the RM-1 murine prostate can...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06867-8 |
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