Blood fluke exploitation of non-cognate CD4+ T cell help to facilitate parasite development.
Schistosoma blood flukes, which infect over 200 million people globally, co-opt CD4+ T cell-dependent mechanisms to facilitate parasite development and egg excretion. The latter requires Th2 responses, while the mechanism underpinning the former has remained obscure. Using mice that are either defec...
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| Main Authors: | Erika W Lamb, Colleen D Walls, John T Pesce, Diana K Riner, Sean K Maynard, Emily T Crow, Thomas A Wynn, Brian C Schaefer, Stephen J Davies |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-04-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000892&type=printable |
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