Blood fluke exploitation of non-cognate CD4+ T cell help to facilitate parasite development.

Blood fluke exploitation of non-cognate CD4+ T cell help to facilitate parasite development.

Schistosoma blood flukes, which infect over 200 million people globally, co-opt CD4+ T cell-dependent mechanisms to facilitate parasite development and egg excretion. The latter requires Th2 responses, while the mechanism underpinning the former has remained obscure. Using mice that are either defec...

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Bibliographic Details
Main Authors: Erika W Lamb, Colleen D Walls, John T Pesce, Diana K Riner, Sean K Maynard, Emily T Crow, Thomas A Wynn, Brian C Schaefer, Stephen J Davies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000892&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000892&type=printable

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