Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant Candida auris

Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant Candida auris

Candida auris has emerged as a problematic fungal pathogen associated with high morbidity and mortality. Amphotericin B (AmB) is the most effective antifungal used to treat invasive fungal candidiasis, with resistance rarely observed among clinical isolates. However, C. auris possesses extraordinary...

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Bibliographic Details
Main Authors: Ehab A. Salama, Yehia Elgammal, Aruna Wijeratne, Nadia A. Lanman, Sagar M. Utturkar, Atena Farhangian, Jianing Li, Brigitte Meunier, Tony R. Hazbun, Mohamed N. Seleem
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Lansoprazole
metabolites
PISA analysis
C. auris
fungal respiration
cytochrome bc1
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2322649
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https://www.tandfonline.com/doi/10.1080/22221751.2024.2322649

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