Intranasal prime-boost RNA vaccination elicits potent T cell response for lung cancer therapy

Abstract The rapid success of RNA vaccines in preventing SARS-CoV-2 has sparked interest in their use for cancer immunotherapy. Although many cancers originate in mucosal tissues, current RNA cancer vaccines are mainly administered non-mucosally. Here, we developed a non-invasive intranasal cancer v...

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Bibliographic Details
Main Authors: Hongjian Li, Yating Hu, Jingxuan Li, Jia He, Guocan Yu, Jiasheng Wang, Xin Lin
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-025-02191-1
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