Identification of anoikis-related subtypes and a risk score prognosis model, the association with TME landscapes and therapeutic responses in hepatocellular carcinoma

Identification of anoikis-related subtypes and a risk score prognosis model, the association with TME landscapes and therapeutic responses in hepatocellular carcinoma

IntroductionAnoikis is a distinct form of programmed cell death, differing from classical apoptosis, and its role in malignant tumor progression, particularly in hepatocellular carcinoma (HCC), remains insufficiently understood. This study aims to elucidate the prognostic significance and therapeuti...

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Main Authors: Xiangyu Zhai, Kecheng Li, Hailing Ding, Yanmei Wu, Xinlu Zhang, Hao Zhang, Huaxin Zhou, Chongzhong Liu, Zili Zhang, Bin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
anoikis
hepatocellular carcinoma
tumor microenvironment
prognostic signature
immunotherapy response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602831/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602831/full

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