Bioguided Identification of Polymethoxyflavones as Novel Vascular Ca<sub>V</sub>1.2 Channel Blockers from Citrus Peel

Bioguided Identification of Polymethoxyflavones as Novel Vascular Ca<sub>V</sub>1.2 Channel Blockers from Citrus Peel

The huge amount of citrus peel produced worldwide represents an economic burden for society. However, this agricultural by-product is a rich source of natural molecules, potentially endowed with interesting pharmacological activities. In this regard, we decided to investigate if the polymethoxyflavo...

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Bibliographic Details
Main Authors: Anna Ramunno, Rosa Maria Vitale, Pietro Amodeo, Carlo Crescenzi, Alice Panti, Paolo Fiorenzani, Michele De Luca, Umile Gianfranco Spizzirri, Donatella Restuccia, Francesca Aiello, Fabio Fusi
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
polymethoxyflavones
Ca<sub>V</sub>1.2 channel blockers
docking studies
multivariate curve resolution
Online Access:https://www.mdpi.com/1420-3049/29/23/5693
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