Rapgef3 modulates macrophage reprogramming and exacerbates synovitis and osteoarthritis under excessive mechanical loading

Rapgef3 modulates macrophage reprogramming and exacerbates synovitis and osteoarthritis under excessive mechanical loading

Summary: Evidence indicates that mechanical loading plays an important role in osteoarthritis (OA) progression, while the specific pathological changes of the synovium under excessive mechanical loading are unclear. Results showed that excessive mechanical loading caused pro-inflammation of synovial...

Full description

Saved in:
Bibliographic Details
Main Authors: Wen Tang, Jian-bin Yin, Ren-gui Lin, Chun-yu Wu, Jia-luo Huang, Jin-jian Zhu, Ling-feng Yang, Guang-ming Li, Dao-zhang Cai, Liang-liang Liu, Yan-li Liu, Hai-yan Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Immunology
Biomechanics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225003918
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2589004225003918

Similar Items