Downregulation of PGK1 promotes lipid peroxidation and suppresses proliferation in cervical cancer revealed by liquid-liquid phase separation-related gene signature

Downregulation of PGK1 promotes lipid peroxidation and suppresses proliferation in cervical cancer revealed by liquid-liquid phase separation-related gene signature

Abstract Cervix cancer is a major health concern globally, being the fourth most prevalent type of cancer among females across the globe. Despite existing preventive measures like cytology and HPV testing, more precise diagnostic and treatment strategies are needed. This study leverages single-cell...

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Bibliographic Details
Main Authors: Beilei Zhang, Zhanghang Li, Zhaojie Yang, Yidan Yin, Mingke Duan, Lei Wang, Qirui Zhan, Fu Wang, Ruifang An
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
Subjects:
Liquid-liquid phase separation
Transcriptome analysis
Single-cell sequencing
PGK1
Cervical cancer
Online Access:https://doi.org/10.1186/s12885-025-14637-4
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https://doi.org/10.1186/s12885-025-14637-4

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