Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in a mouse model of Alzheimer’s disease

Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in a mouse model of Alzheimer’s disease

Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease. Adult hippocampal neurogenesis is reduced in patients with Alzheimer’s disease. Exercise stimulates adult hippocampal neurogenesis in rodents and improves memory and slows cognitive decline in patients with Alzheimer’s di...

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Bibliographic Details
Main Authors: Mackenzie M. Spicer, Jianqi Yang, Daniel Fu, Alison N. DeVore, Marisol Lauffer, Nilufer S. Atasoy, Deniz Atasoy, Rory A. Fisher
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-10-01
Series:Neural Regeneration Research
Subjects:
adult hippocampal neurogenesis
alzheimer’s disease
dentate gyrus
exercise
learning/memory
neural precursor cells
regulator of g protein signaling 6 (rgs6)
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01993
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https://journals.lww.com/10.4103/NRR.NRR-D-23-01993

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