Peptide-directed interference of PD-1/PD-L1 binding increases B lymphocyte function after infectious bursal disease viral infection

Peptide-directed interference of PD-1/PD-L1 binding increases B lymphocyte function after infectious bursal disease viral infection

ABSTRACT: Programmed cell death protein 1 (PD-1)/PD-1 ligand 1 (PD-L1) binding contributes to immune evasion mechanisms responsible for B lymphocyte exhaustion and apoptosis. This facilitates immunosuppression in chronic viral infections, including infectious bursal disease virus (IBDV). Our previou...

Full description

Saved in:
Bibliographic Details
Main Authors: Qiuyu Zhang, Guopeng Sun, Feng Yue, Zhike Liu, Peng Li, Yanping Zhu, Yangzhao Zhu, Ruiyan Niu, Zilong Sun, Xuannian Wang, Gaiping Zhang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Poultry Science
Subjects:
peptide gCK-16
PD-1/PD-L1
infectious bursal disease virus
immunosuppression
B lymphocyte function
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124009684
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S0032579124009684

Similar Items