Untargeted Liquid Chromatography–High-Resolution Mass Spectrometry Metabolomic Investigation Reveals Altered Lipid Content in <i>Leishmania infantum</i> Lacking Lipid Droplet Protein Kinase

Untargeted Liquid Chromatography–High-Resolution Mass Spectrometry Metabolomic Investigation Reveals Altered Lipid Content in <i>Leishmania infantum</i> Lacking Lipid Droplet Protein Kinase

Leishmaniasis is a complex disease caused by different species of <i>Leishmania</i>. To date, no vaccine for humans or ideal therapy has been developed owing to the limited efficacy and toxicity of available drugs, as well as the emergence of resistant strains. Therefore, it is necessary...

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Bibliographic Details
Main Authors: Juliana Martins Ribeiro, Gisele André Baptista Canuto, Alisson Samuel Portes Caldeira, Ezequias Pessoa de Siqueira, Carlos Leomar Zani, Silvane Maria Fonseca Murta, Tânia Maria de Almeida Alves
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Tropical Medicine and Infectious Disease
Subjects:
lipid droplet protein kinase
<i>L. infantum</i>
untargeted metabolomics
liquid chromatography–high-resolution mass spectrometry (LC-HRMS)
Online Access:https://www.mdpi.com/2414-6366/9/9/208
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