Addressing the pathophysiology of venous thrombosis and chronic kidney disease in sickle cell trait using a mouse model

Addressing the pathophysiology of venous thrombosis and chronic kidney disease in sickle cell trait using a mouse model

Abstract: Sickle cell trait (SCT) is present in participants who possess a single copy of the βS-globin gene mutation. Although most affected individuals are asymptomatic, SCT is a well-established risk factor for venous thrombosis and renal complications, including chronic and end-stage kidney dise...

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Main Authors: Fatima Trebak, Mohammad O. Sako, Steven P. Grover, Karnsasin Seanoon, Izabela Pawlinski, Chatphatai Moonla, Michael W. Henderson, Vimal K. Derebail, Dougald M. Monroe, Patrick Ellsworth, Rafal Pawlinski, Malgorzata Kasztan, Nigel S. Key
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925001582
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http://www.sciencedirect.com/science/article/pii/S2473952925001582

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