NF-κB and apoptosis: colorectal cancer progression and novel strategies for treatment

Abstract Colorectal cancer (CRC), the third most prevalent cancer worldwide, presents a significant burden in terms of both mortality and morbidity. The development of CRC is a complex process, driven by a combination of genetic mutations and epigenetic alterations that disrupt normal cellular funct...

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Main Authors: Sina Sadati, Amirreza Khalaji, Ali Bonyad, Sara Khoshdooz, Kosar Sadat Hosseini Kolbadi, Ashkan Bahrami, Mohammad Saeid Moeinfar, Mohammadmatin Morshedi, Amireza Ghamsaraian, Majid Eterafi, Reza Eshraghi, Mahmood Khaksary Mahabady, Hamed Mirzaei
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02734-w
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