Nanoodor Particles Deliver Drugs to Central Nervous System via Olfactory Pathway

Nanoodor Particles Deliver Drugs to Central Nervous System via Olfactory Pathway

Abstract Central nervous system (CNS) disorders confront significant challenges in drug delivery due to the blood–brain barrier (BBB). Inspired by the rapid and precise binding of odor molecules to olfactory receptors (ORs), this research uses thiolated HPMA to construct odor nanoparticles (nanoodor...

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Bibliographic Details
Main Authors: Wei Zhang, Xingwang Ji, Qianyanqiu Zhao, Jinyao Qi, Wen Guo, Gaoshuo Zhang, Yujing Guan, Shenglong Li, Yuling Mao
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
Agomelatine
Brain targeting
Central nervous system disorders
Nanoodor particles
Olfactory pathway
Online Access:https://doi.org/10.1002/advs.202408908
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