Real-time imaging of blood coagulation and angiogenesis during development in a zebrafish model of type I antithrombin deficiency

Real-time imaging of blood coagulation and angiogenesis during development in a zebrafish model of type I antithrombin deficiency

Abstract Severe type I antithrombin (AT) deficiency is considered to cause embryonic lethality. Although several pathological analyses using mice or zebrafish have been attempted, the previous studies did not unveil the detailed mechanism leading to lethality in the early developmental stage. In ord...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuta Imai, Satoru Ozaki, Taiki Noda, Isao Kobayashi, Kayo Sugitani, Satomi Kasashima, Eriko Morishita, Yuhei Araiso
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Antithrombin deficiency
Zebrafish
Genome editing
Thrombosis
Angiogenesis
Online Access:https://doi.org/10.1038/s41598-025-01658-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-01658-z

Similar Items