Two case reports of B-cell lymphopenia associated with IGLL1 variants identified through newborn screening in Ukraine

Before the implementation of newborn screening (NBS), only a few cases of agammaglobulinemia associated with IGLL1 variants had been reported. The IGLL1 gene encodes the surrogate light chain components λ5 and VpreB, which form a crucial part of the pre-B cell receptor complex. A recently published...

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Bibliographic Details
Main Authors: Oksana Boyarchuk, Yaryna Romanyshyn, Ihor Savchak, Volodymyr Kravets, Ivanna Shymanska, Halyna Makukh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1566867/full
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