Analytical Basal-State Model of the Glucose, Insulin, and C-Peptide Systems for Type 2 Diabetes

Analytical Basal-State Model of the Glucose, Insulin, and C-Peptide Systems for Type 2 Diabetes

We present a mechanistic mathematical model of the basal state for type 2 diabetes mellitus (T2DM) in an analytical form and illustrate its use for in silico basal-state and dynamic studies. At the core of the basal-state model is a quartic equation that expresses the basal plasma glucose concentrat...

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Bibliographic Details
Main Authors: Ched C. Chichester, Munekazu Yamakuchi, Kazunori Takenouchi, Teruto Hashiguchi, Drew N. Maywar
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Bioengineering
Subjects:
mechanistic modeling
type 2 diabetes mellitus
basal state
glucose
insulin
C-peptide
Online Access:https://www.mdpi.com/2306-5354/12/5/553
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