Multiomic analysis of lactylation and mitochondria-related genes in hepatocellular carcinoma identified MRPL3 as a new prognostic biomarker

Multiomic analysis of lactylation and mitochondria-related genes in hepatocellular carcinoma identified MRPL3 as a new prognostic biomarker

BackgroundRecent research has highlighted lactate’s crucial role in epigenetic regulation, particularly by influencing histone modifications that drive the initiation and progression of hepatocellular carcinoma (HCC). While mitochondria are known to regulate tumor behavior, the interaction between l...

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Bibliographic Details
Main Authors: Wenya Xing, Yuanzi Zhou, Qiuzi Long, Nan Yi, Gaoyuan Wang, Rongwei Shi, Jinlong Huang, Xindong Yin, Taiyang Zhu, Shibing Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
lactylation
epigenetic regulation
MRPL3
prognostic biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1511958/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1511958/full

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