PathoGD: an integrative genomics approach to primer and guide RNA design for CRISPR-based diagnostics

PathoGD: an integrative genomics approach to primer and guide RNA design for CRISPR-based diagnostics

Abstract Critical to the success of CRISPR-based diagnostic assays is the selection of a diagnostic target highly specific to the organism of interest, a process often requiring iterative cycles of manual selection, optimisation, and redesign. Here we present PathoGD, a bioinformatic pipeline for ra...

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Main Authors: Soo Jen Low, Matthew O’Neill, William J. Kerry, Natasha Wild, Marcelina Krysiak, Yi Nong, Francesca Azzato, Eileen Hor, Lewis Williams, George Taiaroa, Eike Steinig, Shivani Pasricha, Deborah A. Williamson
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07591-1
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https://doi.org/10.1038/s42003-025-07591-1

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