Unlocking the potential of hydrogen deuterium exchange via an iterative continuous-flow deuteration process

Abstract Labelled compounds bearing hydrogen isotopes are keystones in diverse areas constituting a multi-billion dollar global market including drugs, diagnostics, biology, toxicology and smart materials. While hydrogen deuterium exchange (HDE) methods hold promise as relevant tools for the late-st...

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Bibliographic Details
Main Authors: Kevin Tatoueix, Marco Lepron, Cédric Barboux, Marie-Christine Scherrmann, Grégory Pieters, Sophie Feuillastre
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56600-8
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