Fabrication and optimization of freeze-dried isoniazid-loaded poly-ε-caprolactone nanoparticles

Fabrication and optimization of freeze-dried isoniazid-loaded poly-ε-caprolactone nanoparticles

Background: Microfluidic nanoprecipitation followed by freeze-drying would yield uniformly sized, stable nanoparticles by preserving their physicochemical property without compromising therapeutic performance. The isoniazid (INH)-loaded poly-ε-caprolactone (PCL) nanoparticles could be developed usi...

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Bibliographic Details
Main Authors: Eknath Kole, Yuvraj Pawara, Atul Chaudhari, Aniruddha Chatterjee, Jitendra B. Naik
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2025-07-01
Series:ADMET and DMPK
Subjects:
Lyophilization
nanoprecipitation
microreactor
sustained release
pulmonary tuberculosis
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/2774
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