The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism

Liver X receptors (LXRs) have emerged as important regulators of inflammatory gene expression. Previously, we had reported that an LXRα gene promoter polymorphism (-1830 T > C) is associated with systemic lupus erythematosus (SLE). Therefore, we assessed cytokine expression in relation to LXRα po...

Full description

Saved in:
Bibliographic Details
Main Authors: Hyoun-Ah Kim, Wook-Young Baek, Mi-Hwa Han, Ju-Yang Jung, Chang-Hee Suh
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/6217548
Tags: Add Tag
No Tags, Be the first to tag this record!