Computational analysis of serum-derived extracellular vesicle miRNAs in juvenile sheep model of single stage Fontan procedure

Computational analysis of serum-derived extracellular vesicle miRNAs in juvenile sheep model of single stage Fontan procedure

Patients with single ventricle heart defects requires a series of staged open-heart procedures, termed Fontan palliation. However, while lifesaving, these operations are associated with significant morbidity and early mortality. The attendant complications are thought to arise in response to the abn...

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Main Authors: Hyun-Ji Park, John M. Kelly, Jessica R. Hoffman, Felipe Takaesu, William Schwartzman, Anudari Ulziibayar, Takahiro Kitsuka, Eric Heuer, Asigul Yimit, Raphael Malbrue, Cole Anderson, Adrienne Morrison, Aymen Naguib, Christopher Mckee, Andrew Harrison, Brian Boe, Aimee Armstrong, Arash Salavitabar, Andrew Yates, Toshiharu Shinoka, Sergio Carrillo, Christopher K. Breuer, Michael E. Davis
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Extracellular Vesicle
Subjects:
Fontan model
Hemodynamics
Extracellular vesicle
RNA sequencing
MiRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2773041722000087
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http://www.sciencedirect.com/science/article/pii/S2773041722000087

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