Potential ability of circulating INSL3 level for the prediction of ovarian reserve and IVF success as a novel theca cell–specific biomarker in women with unexplained infertility and diminished ovarian reserve

Potential ability of circulating INSL3 level for the prediction of ovarian reserve and IVF success as a novel theca cell–specific biomarker in women with unexplained infertility and diminished ovarian reserve

Abstract Background Insulin-like peptide (INSL3), belonging to the insulin-like peptide family, is produced by theca interna cells within antral follicles and the corpora lutea. It is hypothesized that INSL3 is integral to the initial development and function of antral follicles, specifically throug...

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Bibliographic Details
Main Authors: Pinar Ozcan, F. Sezer, A. Altun, C. Yildiz, H. T. Timur, E. C. Keles, O. Dural, H. S. Taha, E. Saridogan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Reproductive Biology and Endocrinology
Subjects:
Insulin-like peptide 3
Ovarian reserve
In vitro fertilization
Diminished ovarian reserve
Online Access:https://doi.org/10.1186/s12958-025-01367-2
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https://doi.org/10.1186/s12958-025-01367-2

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