Improved survival and neurological outcomes with lysophosphatidylcholine supplementation in severe cardiac arrest model

Improved survival and neurological outcomes with lysophosphatidylcholine supplementation in severe cardiac arrest model

Cardiac arrest (CA) results in a loss of blood circulation, leading to whole-body ischemia-reperfusion injuries. A deficiency in plasma lysophosphatidylcholine (LPC) levels has been observed in both human patients and rat models and is implicated in organ dysfunction following CA. Building on previo...

Full description

Saved in:
Bibliographic Details
Main Authors: Muhammad Shoaib, Mitsuaki Nishikimi, Rishabh C. Choudhary, Tsukasa Yagi, Kei Hayashida, Tai Yin, Blanca B. Espin, Lance B. Becker, Junhwan Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
cardiac arrest
lysophosphatidylcholine
ischemia-reperfusion injury
mass spectrometry
outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1587776/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2025.1587776/full

Similar Items