Simple supplementation of serum-free medium produces gametocytes of Plasmodium falciparum that transmit to mosquitoes

Abstract Background Human serum is a major component of Plasmodium falciparum culture medium, and can be replaced with AlbuMAX™ II, a lipid-rich bovine serum albumin, for asexual cultures. However, gametocytes produced without serum are poorly infective to mosquitoes. Serum suffers from high cost, l...

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Bibliographic Details
Main Authors: Sabyasachi Pradhan, Prince Chigozirim Ubiaru, Lisa Ranford-Cartwright
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Malaria Journal
Subjects:
Online Access:https://doi.org/10.1186/s12936-024-05094-8
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