Rhizoma coptidis Inhibits LPS-Induced MCP-1/CCL2 Production in Murine Macrophages via an AP-1 and NF𝜅B-Dependent Pathway

Rhizoma coptidis Inhibits LPS-Induced MCP-1/CCL2 Production in Murine Macrophages via an AP-1 and NF𝜅B-Dependent Pathway

Introduction. The Chinese extract Rhizoma coptidis is well known for its anti-inflammatory, antioxidative, antiviral, and antimicrobial activity. The exact mechanisms of action are not fully understood. Methods. We examined the effect of the extract and its main compound, berberine, on LPS-induced i...

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Main Authors: Andrew Remppis, Florian Bea, Henry Johannes Greten, Annette Buttler, Hongjie Wang, Qianxing Zhou, Michael R. Preusch, Ronny Enk, Robert Ehehalt, Hugo Katus, Erwin Blessing
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2010/194896
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http://dx.doi.org/10.1155/2010/194896

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