An in silico and in vitro approach for understanding CDK2 expression pattern and prognostic implications in breast cancer
Background: CDK2 (Cyclin-Dependent Kinase 2) is a Ser/Thr kinase that regulates cell cycle progression by promoting the G1/S transition and initiating DNA synthesis through its interaction with cyclins E and A. Unchecked cell growth, DNA damage, and protein deterioration are caused by an abnormally...
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| Main Authors: | Fatima Manhas, Shazia Sofi, Asma Jan, Nusrat Jan, Manzoor Ahmad Mir |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625001900 |
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