An in silico and in vitro approach for understanding CDK2 expression pattern and prognostic implications in breast cancer

Background: CDK2 (Cyclin-Dependent Kinase 2) is a Ser/Thr kinase that regulates cell cycle progression by promoting the G1/S transition and initiating DNA synthesis through its interaction with cyclins E and A. Unchecked cell growth, DNA damage, and protein deterioration are caused by an abnormally...

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Bibliographic Details
Main Authors: Fatima Manhas, Shazia Sofi, Asma Jan, Nusrat Jan, Manzoor Ahmad Mir
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625001900
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