Computational modeling of cancer cell metabolism along the catabolic-anabolic axes
Abstract Abnormal metabolism is a hallmark of cancer, this was initially recognized nearly a century ago through the observation of aerobic glycolysis in cancer cells. Mitochondrial respiration can also drive tumor progression and metastasis. However, it remains largely unclear the mechanisms by whi...
Saved in:
| Main Authors: | Javier Villela-Castrejon, Herbert Levine, Benny A. Kaipparettu, José N. Onuchic, Jason T. George, Dongya Jia |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00525-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Clinical Implications of Catabolic and Anabolic Bone Changes in Psoriatic Arthritis
by: Georg Schett
Published: (2024-01-01) -
Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.
by: Khalid S Mohammad, et al.
Published: (2009-01-01) -
Effects of anabolic and catabolic nutrients on woody plant encroachment after long-term experimental fertilization in a South African savanna.
by: Anthony J Mills, et al.
Published: (2017-01-01) -
Aberrant anabolism hinders constructive metabolism of chondrocytes by pharmacotherapy in osteoarthritis
by: Raquel Largo, et al.
Published: (2025-03-01) -
Axing the Rainbow
by: Irina Turner
Published: (2019-07-01)