Bio-inspired manganese-catalyzed deaminative hydroxylation of benzyl amines to corresponding alcohols

Abstract Direct conversion of amines to corresponding alcohols is challenging even under harsh reaction conditions. Inspired by enzymatic transamination, we present a transamination borrowing-hydrogen strategy that enables the direct and selective Mn-catalyzed deaminative hydroxylation of benzylamin...

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Bibliographic Details
Main Authors: Jiale Ji, Shiliang Wang, Zhaowen Dai, Yinghao Huo, Limin Wang, Qingshu Zheng, Tao Tu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61989-3
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